产品货号：
Z24081
中文名称：
PKLR抗体
英文名称：
Anti-PKLR Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PKLR Antibody |
| 指标别名 | PK1;PKL;PKLR;PKR;PKRL;Pyruvate kinase 1;Pyruvate kinase isozymes R/L;pyruvate kinase;liver and RBC;R type/L type pyruvate kinase;Red cell/liver pyruvate kinase;RPK |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | PKLR |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human PKLR (522-552aa EAIWADDVDRRVQFGIESGKLRGFLRVGDLV),different from the related mouse sequence by one amino acid,and identical to the rat sequence. |
| 实际分子量 | 62KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Pyruvate kinase isozymes R/L is an enzyme that in humans is encoded by the PKLR gene.It is mapped to 1q21.The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP,which is the rate-limiting step of glycolysis.Defects in this enzyme,due to gene mutations or genetic variations,are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA).Multiple transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | P30613 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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